In 30 years of off and on baseball simulation I have never had a pitcher of mine throw a no hitter. I've probably played over 3,000 games and never had it happen.
Still have not, because Reds starting pitcher Mike Leake decided to go 2-2 against Shelby Miller who gave up only those 2 hits while striking out 14. Not a heartbreak like a no hitter broken up in the 9th, but still...