Ramos > Realmuto in the game. And Pedro is awesome
You desperately need infield help. Machado is borderline unplayable at SS, but solid at 3B. Fatigue is high in the league, so each infielder needs to sit for ~15 games a season, and I can't imagine how bad 15 games of Bryant at SS or even 2B would hurt you. Doesn't have to be a star, but someone like a Simmons, Tony Fernandez, Rookie Tulo, etc... who can give you gold glove caliber D around the infield. Or if you want more offense, someone like Adames or Bo Bichette are playable as backups.
The back end of the rotation could probably use some help too, as those low diamond live starters are a bit underwhelming. Although with Pedro, now you can run Sale-Pedro-Verlander-Dierker as a strong top-4, so the #5 arm matters less. Bullpen could probably also use a boost - adding in Diaz or Treinen or a good historical closer would do wonders.