I had injuries set to "normal" for awhile and it got to be like a M.A.S.H. unit so I had to turn it down. "Low" seems about right to me. The bad thing about the normal setting is it takes a season or two to really hit you. It started out as a lot of small DTD injuries and that seemed ok, but here's the thing; every time a player is injured they become more injury prone. So after a season or two, everybody is either Fragile or Wrecked and then it gets really bad. Half the team was on the 60 day DL.