So just applied the new hotfix and started a game from the MLB.quickstart file
The quickstart loaded fine, except when I looked at the financials, specifically the financials for independent leagues, more specifically the Frontier League... this is what I saw
and after a couple of restarts and checking different things, I came to realize that if the roster size is changed to 25 instead of 24 the financials look like this
After checking a few other things I also realized that any independent with an active roster of 24 or less is getting a $708 million and change predicted payroll per team... I believe this might be a bug you may need to address
EDIT: I just realized I posted the pictures of my split version of the American Association.... but no matter, all Leagues have this financial issue with an active roster of 24 or less unless they have a secondary roster (e.g. the MLB 40-Man Roster)