I honestly thought we'd never have another 400 game winner. It just barely happened, but Lou Schlettler notched wins 400 and 401 in 1926, wrecking his other stats in the process but showing amazing heart and determination.
A three-time world Champion with those amazing White Sox teams of the 1910s (and one-time World Series MVP), Schletter was pretty good even up to 1925, but the push to come back one last year seemed to have been too much for him. Still, he's a sure-fire Hall of Famer, and who knows? Maybe there'll be a bit more in the tank.