I think I finally figured it out. I think what was throwing everything out of whack was that I had 2 regular starters on an odd rotation. One player going out every 3rd game and another every 10th. Not sure why that was set by default because I know I didn't set it up that way.
Is there a way to set up multiple versions of a lineup when those "scheduled" off days for certain players come up? I think it's a bit annoying on auto-play when the computer reshuffles the lineup seemingly at random when giving a starter the occasional day off.
Thanks for all the help everybody.