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1. Absolutely.
2. They could email their picks to you and you could input them into the game. A new league file would need to be uploaded after each round so everyone would know who's still available. When a cpu team came up, just do 'cpu pick'.
3. Ftp is the method by which you would upload the zipped league file and all other HTML files for the league to the website.
4. Commish would make all changes to the 'master' league file (your OOTP game) and then zip it up and put it up as a league file. The other owners would get it, unzip it to their OOTP game and theirs would match yours.
5. Only lineups and roster moves are exported. The only person that could 'cheat' by changing players would be the commish (you).
Hope this helps, but my advice to you as a newbie is to get into an online league and learn the ins and outs of that before you take on the task of running a league of your own.
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